Bilateral diffuse iris atrophy after the use of oral clarithromycin
Tranos P, Nasr MB, Asteriades S, Vakalis A, Georgalas I
Cutan Ocul Toxicol. 2014 Mar;33(1):79-81. doi: 10.3109/15569527.2013.802696. Epub 2013 Jun 14
PMID: 23763291
Abstract
Purpose:
To report a newly recognised advert event of clarithromycin.
Methods:
Retrospective, case report.
Results:
A 30-year old female referred to our centre with bilateral diffuse iris atrophy after the use of oral clarithromycin for a pulmonary infection.
Conclusions:
Bilateral acute depigmentation of the iris is a new clinical entity. Iris transillumination and sphincter paralysis are recognised adverse effects of oral antibiotic therapy, but to our knowledge no other publication has referred to uveitis-like syndrome due to oral administration of clarithromycin.
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Source: Pubmed